This is a 47 year old man who presents with a scaly nodule on the shoulder.
This is an extremely rare soft tissue sarcoma. About half of reported cases arise in a pre-existing glomus tumor, although this is not necessary for a diagnosis. The tumor is defined by the following:
Size>2 cm and deeply located
As in all glomus tumors, including this case, the tumor cells will stain strongly positive for smooth muscle actin. The prognosis is guarded with 38% of reported cases, that meet the above defined critera, developing metastases.
Addendum: Less than one week after this case was received, a second malignant glomus tumor on a different patient was also reviewed in consultation.
The Doctor's Doctor-Glomus Tumors
Am J Surg Pathol 2001;25:1
Archived Case Studies
Last Updated March 15, 2005
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